Selected Projects
This page contains work samples from my post-secondary studies and personal projects I have completed since graduation. These include research papers, coding competitions, and useful programming modules.
Overview
For my MDS capstone requirement, I conducted an independent study on the polygenic risk scoring (PRS) of autism under the supervision of Dr. Jonathan Terhorst. This study lasted from May 2025 to August 2025. Although scientists have made great progress in identifying genes that cause autism through the Human Genome Diversity Project, the vast majority of samples in the HGDP are of European ancestry. My project evaluated the portability of the PRS for autism across underreperesented populations.
Useful Links
GitHub Proposal ReportTech Stack
Overview
I developed a direct spatial interpolation method for solving a set of 25-dimensional coordinates given 26+ Euclidean distances to known data points.
Although this method could be used for any multi-dimensional data, our application focuses specifically on PCA-derived genetic coordinates. Global25 (G25)
is a coordinate system created from the EIGENSOFT and smartpca software and can be found here.
I collaborated with GitHub user AimSmall37, who shares a common interest in population genetics and genealogy. He implemented the multilateral interpolation mode and created the HTML for the app. I proposed the direct linear solver method, which he integrated into the web app.
Use Cases for the Coordinate Estimator:
1. Creating synthetic data
2. Estimating Global25 coordinates for a deceased or untested relative
3. Studying population structures and identifying patterns
View Application View Python ScriptTech Stack
Tech Stack
